Affordable and real‑time antimicrobial resistance prediction from multimodal electronic health records

Affordable and real‑time antimicrobial resistance prediction from multimodal electronic health records

The spread of antimicrobial resistance (AMR) leads to challenging complications and losses of humanlives plus medical resources, with a high expectancy of deterioration in the future if the problem isnot controlled. From a machine learning perspective, datadriven models could aid clinicians andmicrobiologists by anticipating the resistance beforehand. Our study serves as the first attempt toharness deep learning (DL) techniques and the multimodal data available in electronic health records(EHR) for predicting AMR. In this work, we utilize and preprocess the MIMICIV database extensivelyto produce separate structured input sources for timeinvariant and timeseries data customized tothe AMR task. Then, a multimodality fusion approach merges the two modalities with clinical notes todetermine resistance based on an antibiotic or a pathogen. To efficiently predict AMR, our approachbuilds the foundation for deploying multimodal DL techniques in clinical practice, leveraging theexisting patient data.

 

Paper Link: https://rdcu.be/dN7vh